The restoration of the basic regulatory mechanisms appears to be an important precondition for specific immunotherapy to reach its optimal effect.
According to the concept that cancer starts as a locally confined growth, all measures concentrated on the tumor alone seem causal and exhaustive.
On the basis of the Combined concept, however, cancer is considered a systemic disease from the onset and the tumor as its late stage symptom. Therefore, it is necessary to apply two lines of approach which are of equal importance and complement each other: local and systemic treatment. The CIC program places equal importance on the removal of the tumor itself and on the causes and conditions leading to the body's tendency to develop malignant tumors.
World Health Organization (WHO) claimed that "cancer as a chronic disease. How to turn the cancer into a controlled chronic disease? CIC play an important role.